18. Antonine Plague, 165 AD (Over 5,000,000 Deaths)
Europe
5 million people died as a result of the Antonine Plague, which to this day still doesn’t have an official cause. Alternatively known as the Plague of Galen, European cities were most affected, though at the time it was hard for researchers to distinguish between these deaths and people dying of smallpox and measles. Soldiers brought the unknown disease back from battles in Rome, and millions died, including nearly the entire Roman army. Sometimes it’s the enemy you can’t see that causes more problems than the one can
Antonie Plague
19. Tuberculosis, 19th Century (Over 2,000,000 Deaths)
Euorope
TB is a well-known disease that has been around for centuries, with the first recorded cases coming from Egyptian mummies back in 3000 BC. The 19th and 20th centuries were plagued by the disease, attacking the lungs and other parts of the body, before taking out its victims through the brain. Up to 90% of European populations in urban cities had been affected by TB by the end of the 19th century, with 80% of people dying as a result of this. These days, TB is rare in developed nations, second only to HIV/AIDS. Millions still contract the disease each year, especially those with weak immune systems, albeit more closely linked to people who suffer from HIV/AIDS, which weakens your immune system substantially.
Tuberculosis
