6. Smallpox, 1949-1980, (400,000 Deaths Per Year)
Worldwide
Smallpox is well known around the world as something that wiped out hundreds of millions of people within the span of a few centuries. Some may be quick to point the finger to other species, but unfortunately, this disease is only carried by humans. Coming in a range of types, with this virus you can expect to get a fever, rash and even blistering. Luckily, in modern times it is officially considered eradicated, thanks in large due to a global effort to get vaccinations done. No cases have been reported since 1979, but naturally, this can change at any time.
Smallpox
7. Dengue (22,000 Deaths Per Year)
Worldwide
Dengue is a nasty tropical disease that masquerades as an infection, causing high fever and headaches, and sometimes even internal bleeding. Fortunately, it is treatable and non-contagious, but it may not be as simple as that. There are no vaccinations available and it is easy to pick this up while traveling, especially if you get bitten by a mosquito. 33% of the world’s population is subsequently at risk, with over 100 million cases being reported each year. Bug spray, anyone?
Dengue
